Authors: Jеtmire Alimani-Jakupi, Marija Nakova, Ferizate Haxhirexha, Kenan Ferati, Lindihana Emini, Marija Stojanova, Sabtim Cerkezi, Zana Jusuf

DOI: To be acquired

Keywords: Oral lichen planus, hypertension, diabetes, precipitating factors.

ABSTRACT

Introduction: Oral lichen planus (OLP) is a chronic inflammatory disease, the cause of which remains unknown. In the last few years, significant advances have been made in understanding the mechanisms involved in the pathogenesis of the disease.
Aim: The purpose of this investigation was to describe the clinical and epidemiological characteristics of lichen planus.
Materials and methods: A total of 147 charts of patients with histologically confirmed OLP were collectedfrom 5 years from Private health Institution”preventiva dental” Gostivar, Private health Institution “Apolon”, Private health Institution “Viva DENT” Gostivar and Private health Institution “Dentalcair”, Skopje. Patients of either gender aged above 12 years, fulfilling the diagnostic criteria for OLP were enrolled for study History regarding the onset and duration,symptoms, addictions was elicited followed by oral, cutaneous and systemic examination. Biopsy was taken when the diagnosis was doubtful or malignancy was suspected. The data were analyzed using SPSS software version 11.0 for frequency and percentage.
Results: Of the 147 patients, 62.9 % were females and 37,1% were males. The most common clinical presentation was the reticular type from topographic aspects which is localized bilaterally in the buccal mucosa between retromolar region and masticator line. Accompanying comorbidities are hypertension 58,5 % and Diabetes 21,77%.
Conclusion: From the results we can conclude that lichen planus is a dermatology condition that can present on the skin, oral cavity or in the combination skin and oral mucosis. Skin involvement of lichen planus was found in 40,17% .